Gene

Mbtd1

Species
Mus musculus
Symbol
Mbtd1
Name
mbt domain containing 1
Synonyms
  • AA408199
  • AI194990
Biotype
protein coding gene
Automated Description
Predicted to enable NuA4 histone acetyltransferase complex binding activity; chromatin binding activity; and methylated histone binding activity. Acts upstream of or within embryonic skeletal system development. Predicted to be part of NuA4 histone acetyltransferase complex and nucleosome. Predicted to be active in nucleus and site of double-strand break. Is expressed in several structures, including cerebral cortex; early conceptus; gonad; neural retina; and skeletal muscle tissue. Orthologous to human MBTD1 (mbt domain containing 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality and severe abnormalities in hematopoietic stem cell function and skeletal formation. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12247
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
93.78M93.79M93.80M93.81M93.82M93.83M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions