Gene

Clic1

Species
Mus musculus
Symbol
Clic1
Name
chloride intracellular channel 1
Synonyms
  • Clcp
  • G6
Biotype
protein coding gene
Automated Description
Predicted to enable chloride channel activity. Acts upstream of or within positive regulation of osteoblast differentiation and regulation of mitochondrial membrane potential. Located in mitochondrion and nucleus. Is expressed in brain; early conceptus; and heart valve. Orthologous to human CLIC1 (chloride intracellular channel 1).
MGI Description
PHENOTYPE: Mice homozygous for disruptions in this gene display abnormal platelet number, activation and aggregation and prolonged bleeding time. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43920
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
35.270M35.271M35.272M35.273M35.274M35.275M35.276M35.277M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions