DNA segment, Chr 17, Wayne State University 104, expressed
Biotype
protein coding gene
Automated Description
Involved in several processes, including positive regulation of endothelial cell proliferation; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Located in extracellular space. Is expressed in embryo and extraembryonic component. Orthologous to human MYDGF (myeloid derived growth factor).
MGI Description
PHENOTYPE: Mice homozygous for a null mutation display normal cardiac and vascular development but develop larger myocardial infactions with reduced angiogenesis and increased scarring. [provided by MGI curators]