Gene

Mycbp2

Species
Mus musculus
Symbol
Mycbp2
Name
MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms
  • AU023734
  • AW107953
Biotype
protein coding gene
Automated Description
Enables identical protein binding activity. Involved in several processes, including central nervous system projection neuron axonogenesis; circadian regulation of gene expression; and positive regulation of protein ubiquitination. Acts upstream of or within several processes, including branchiomotor neuron axon guidance; negative regulation of protein catabolic process; and regulation of cytoskeleton organization. Located in axon and microtubule cytoskeleton. Is expressed in nervous system and neural retina. Orthologous to human MYCBP2 (MYC binding protein 2).
MGI Description
PHENOTYPE: Mice homozygous for a targeted allele exhibit neonatal lethality, defective diaphragm innervation, abnormal brain morphology and defective axonal guidance. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45943
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
103.36M103.38M103.40M103.42M103.44M103.46M103.48M103.50M103.52M103.54M103.56M103.58M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions