Version: 8.0.0Date: Tue Jan 28 2025
Gene
Myrip
- Species
- Mus musculus
- Symbol
- Myrip
- Name
- myosin VIIA and Rab interacting protein
- Synonyms
- A230081N12Rik
- RIKEN cDNA A230081N12 gene
- Biotype
- protein coding gene
- Automated Description
- Enables cytoskeletal protein binding activity; protein kinase A binding activity; and small GTPase binding activity. Predicted to be involved in positive regulation of insulin secretion. Predicted to act upstream of or within vesicle transport along actin filament. Located in several cellular components, including actin cytoskeleton; melanosome; and photoreceptor outer segment. Part of exocyst. Is expressed in several structures, including gut; heart; lung; male reproductive gland or organ; and nervous system. Orthologous to human MYRIP (myosin VIIA and Rab interacting protein).
- MGI Description
- PHENOTYPE: Mice homozygous for a null allele exhibit glucose intolerance, decreased insulin secretion, and abnormal insulin granule localization in beta-cells. [provided by MGI curators]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR14555
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Gene | Association | Disease Qualifier | Disease | Evidence | Source | Based On | References |
|---|---|---|---|---|---|---|---|
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Sequence Feature Viewer
- Genome location
- Chr9:120132996...120305167 + (172.17 kb)
- Assembly version
- GRCm39
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