Gene

Hexim1

Species
Mus musculus
Symbol
Hexim1
Name
hexamethylene bis-acetamide inducible 1
Synonyms
  • 7330426E13Rik
  • cardiac lineage protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including 7SK snRNA binding activity; P-TEFb complex binding activity; and cyclin-dependent protein serine/threonine kinase inhibitor activity. Acts upstream of or within heart development and negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; heart and pericardium; hindgut dorsal mesentery; and sensory organ. Orthologous to human HEXIM1 (HEXIM P-TEFb complex subunit 1).
MGI Description
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit prenatal lethalilty associated with dilated cardiomyopathy. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13469
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
103.0075M103.0080M103.0085M103.0090M103.0095M103.0100M103.0105M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions