Gene

Rab8b

Species
Mus musculus
Symbol
Rab8b
Name
RAB8B, member RAS oncogene family
Synonyms
  • D330025I23Rik
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including GDP binding activity; GTPase activity; and TPR domain binding activity. Predicted to be involved in several processes, including endocytic recycling; positive regulation of corticotropin secretion; and protein import into peroxisome membrane. Located in mitochondrion. Is expressed in brain; liver; and small intestine. Orthologous to human RAB8B (RAB8B, member RAS oncogene family).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit no overt abnormalities and normal survival. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47980
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
no abnormal phenotype detected
Showing 1 - 1 of 1 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
Rab8atm1.2Aha/Rab8atm1.2Aha Rab8btm1.2Aha/Rab8btm1.2Aha [background:] involves: BALB/cJ * C57BL/6 * SJL
  • abnormal small intestinal microvillus morphology
  • postnatal lethality, complete penetrance
MGI
Rab8btm1.2Aha/Rab8btm1.2Aha [background:] involves: BALB/cJ * C57BL/6 * SJL
  • no abnormal phenotype detected
MGI
Showing 1 - 2 of 2 rows
per page

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
66.76M66.77M66.78M66.79M66.80M66.81M66.82M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

21 interactor genes based on 22 annotations
Rab8b molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
BIRC6Homo sapiens
protein
  • anti tag coimmunoprecipitation
PMID:18329369
protein
BIRC6Homo sapiens
protein
  • fluorescence microscopy
PMID:18329369
protein
CALM1Homo sapiens
protein
  • affinity chromatography technology
PMID:16512683
protein
Gdi1Mus musculus
protein
  • biochemical
PMID:32325033
protein
Gdi2Mus musculus
protein
  • biochemical
PMID:32325033
protein
HttMus musculus
protein
  • affinity chromatography technology
PMID:22794259
protein
Itgb1Mus musculus
protein
  • biochemical
PMID:32325033
protein
JupMus musculus
protein
  • biochemical
PMID:32325033
protein
Ppp1r9bMus musculus
protein
  • affinity chromatography technology
PMID:30562941
protein
Prrt2Mus musculus
protein
  • affinity chromatography technology
PMID:36808153
Showing 1 - 10 of 22 rows
per page

Genetic Interactions

No data available