Gene

Arhgap25

Species
Mus musculus
Symbol
Arhgap25
Name
Rho GTPase activating protein 25
Synonyms
  • A130039I20Rik
  • RGD1562105
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase activator activity. Predicted to be involved in actin filament organization; negative regulation of small GTPase mediated signal transduction; and phagocytosis, engulfment. Predicted to be active in phagocytic cup. Is expressed in brain; cerebral cortex ventricular layer; pharyngo-tympanic tube; and vibrissa. Orthologous to human ARHGAP25 (Rho GTPase activating protein 25).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered leukocyte transendothelial migration. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15228
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
87.44M87.45M87.46M87.47M87.48M87.49M87.50M87.51M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions