Gene

Nmnat2

Species
Mus musculus
Symbol
Nmnat2
Name
nicotinamide nucleotide adenylyltransferase 2
Synonyms
  • AI843915
  • D030041I09Rik
Biotype
protein coding gene
Automated Description
Predicted to enable nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; and protein ADP-ribosyltransferase-substrate adaptor activity. Predicted to be involved in NAD biosynthetic process and negative regulation of cytoplasmic translation. Located in late endosome; synapse; and trans-Golgi network. Is expressed in alimentary system; nervous system; and sensory organ. Orthologous to human NMNAT2 (nicotinamide nucleotide adenylyltransferase 2).
MGI Description
PHENOTYPE: Mice homozygous for a gene trap or transposon inserted allele exhibit perinatal lethality, distended bladders, atelectasis and loss of axon integrity. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12039
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

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      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCm39
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            152.84M152.86M152.88M152.90M152.92M152.94M152.96M152.98M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Nmnat2 molecule type
            Interactor gene
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              Genetic Interactions

              Nmnat2 role
              Nmnat2 genetic perturbation
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