Gene

Mir126a

Species
Mus musculus
Symbol
Mir126a
Name
microRNA 126a
Synonyms
  • microRNA 126
  • Mir126
Biotype
miRNA gene
Automated Description
Acts upstream of or within several processes, including cellular response to estrogen stimulus; hematopoietic stem cell differentiation; and long-term synaptic potentiation. Located in synapse. Is expressed in several structures, including cardiovascular system; genitourinary system; retina; spleen; and yolk sac blood vessel. Orthologous to human MIR126 (microRNA 126).
MGI Description
PHENOTYPE: Mice with a conditional knock-out in CD4+ T cells exhibit aggravated psoriasis-like dermatitis in response to imiquimod with increased Th1 and Th17 cell infiltration in spleen. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
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Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
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    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCm39
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          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Mir126a molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
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            Genetic Interactions

            Mir126a role
            Mir126a genetic perturbation
            Interactor gene
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            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
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