Gene

Syna

Species
Mus musculus
Symbol
Syna
Name
syncytin a
Synonyms
  • gene model 52, (NCBI)
  • Gm52
Biotype
protein coding gene
Automated Description
Acts upstream of or within labyrinthine layer development and myoblast fusion. Predicted to be located in plasma membrane. Is expressed in several structures, including extraembryonic component; ganglia; heart ventricle; musculoskeletal system; and placenta. Orthologous to human ERVFRD-1 (endogenous retrovirus group FRD member 1, envelope).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality between E11.5 and E14.5 associated with defective placental layrinth formation, impaired placental transport, and increased trophoblast cells. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10424
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
134.5870M134.5872M134.5874M134.5876M134.5878M134.5880M134.5882M134.5884M134.5886M134.5888M134.5890M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions