Predicted to be involved in erythrocyte differentiation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; retina; submandibular gland primordium; and thymus primordium. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type Ib. Orthologous to human CDIN1 (CDAN1 interacting nuclease 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele show normal blastocyst formation but exhibit complete embryonic lethality by E7.5. [provided by MGI curators]