Version: 8.0.0
Date: Tue Jan 28 2025
Ttll12
Mus musculusMGI:3039573
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Ttll12

Species
Mus musculus
Symbol
Ttll12
Name
tubulin tyrosine ligase-like family, member 12
Synonyms
  • BC055368
  • cDNA sequence BC055368
Biotype
protein coding gene
Automated Description
Predicted to enable H4K20me3 modified histone binding activity and tubulin binding activity. Predicted to be involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in liver; medulla oblongata basal plate mantle layer; metanephros; submandibular gland primordium; and thymus primordium. Orthologous to human TTLL12 (tubulin tyrosine ligase like 12).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46088
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Download all Alleles/Variants for all genes of the species

      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCm39
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Ttll12 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Ttll12 role
            Ttll12 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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