Gene

Ccdc42

Species
Mus musculus
Symbol
Ccdc42
Name
coiled-coil domain containing 42
Synonyms
  • A530001H01Rik
  • RGD1565925
Biotype
protein coding gene
Automated Description
Involved in spermatid development. Acts upstream of or within acrosome assembly; centrosome cycle; and cilium assembly. Located in several cellular components, including microtubule cytoskeleton; sperm head-tail coupling apparatus; and sperm principal piece. Orthologous to human CCDC42 (coiled-coil domain containing 42).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele are viable and developmentally normal with no overt behavioral deficits. Males exhibit defects in the number and location of the sperm head-tail coupling apparatus, lack flagellated sperm, and are sterile. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21683
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
68.478M68.479M68.480M68.481M68.482M68.483M68.484M68.485M68.486M68.487M68.488M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions