Used to study DiGeorge syndrome; atrial heart septal defect 1; and atrioventricular septal defect.
MGI Description
PHENOTYPE: Homozygotes for this ENU-induced mutation exhibit cardiovascular and craniofacial anomalies, such as persistent truncus arteriosis, atrial septal defect, micrognathia, and flattened snout. Other abnormalities include perinatal lethality, lowered ear position, thymus hypoplasia and short limbs. [provided by MGI curators]