Predicted to enable GTPase activator activity. Acts upstream of or within cilium assembly and protein transport. Is active in Golgi apparatus; cilium; and glutamatergic synapse. Is expressed in several structures, including brain; genitourinary system; inner ear; skin; and spinal cord. Orthologous to human ELMOD1 (ELMO domain containing 1).
MGI Description
PHENOTYPE: Mice homozygous for a spontaneous allele exhibit circling, absent startle reflex, deafness, organ of Corti degeneration and abnormal cochlear hair stereociliary bundle.
[provided by MGI curators]