Gene

Gapt

Species
Mus musculus
Symbol
Gapt
Name
Grb2-binding adaptor, transmembrane
Synonyms
  • 9830130M13Rik
  • RIKEN cDNA 9830130M13 gene
Biotype
protein coding gene
Automated Description
Acts upstream of or within B cell homeostasis and B cell proliferation involved in immune response. Predicted to be located in Golgi apparatus and plasma membrane. Orthologous to human GAPT (GRB2 binding adaptor protein, transmembrane).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit increased B cell proliferation, marginal zone B cell numbers and concentrations of IgM, IgG2b and IgG3. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR37350
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
110.4895M110.4900M110.4905M110.4910M110.4915M110.4920M110.4925M110.4930M110.4935M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions