Acts upstream of or within B cell homeostasis and B cell proliferation involved in immune response. Predicted to be located in Golgi apparatus and plasma membrane. Orthologous to human GAPT (GRB2 binding adaptor protein, transmembrane).
MGI Description
PHENOTYPE: Mice homozygous for a null allele exhibit increased B cell proliferation, marginal zone B cell numbers and concentrations of IgM, IgG2b and IgG3. [provided by MGI curators]