Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; miRNA-mediated post-transcriptional gene silencing; and neuron development. Is expressed in several structures, including gonad; gut; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and autosomal dominant nonsyndromic deafness 50. Orthologous to human MIR96 (microRNA 96).
MGI Description
PHENOTYPE: Mice homozygous and heterozygous for an ENU-induced mutation exhibit hearing loss associated with hair cell degeneration. [provided by MGI curators]