Gene

nad

Species
Mus musculus
Symbol
nad
Name
spontaneous neuroaxonal dystrophy
Synonyms
None
Biotype
heritable phenotypic marker
Automated Description
Used to study neurodegeneration with brain iron accumulation 2a.
MGI Description
PHENOTYPE: As early as 3 weeks of age homozygotes show signs of sensory axonopathy (clasping reflex and ataxia) which progress to paraparesis and morbidity by 6 months of age. Large swollen axons (spheroids) are noted in the brainstem and spinal cord. Males fail tobreed, likely due to hindlimb muscle atrophy. [provided by MGI curators]
Cross References
Not Available
Additional Information
Literature

Orthology

Gene tree
Not Available

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

No data available

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions