Version: 8.0.0
Date: Tue Jan 28 2025
MF5L6
Mus musculusMGI:6119616
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

MF5L6

Species
Mus musculus
Symbol
MF5L6
Name
modifier of Factor 5 Leiden 6
Synonyms
None
Biotype
heritable phenotypic marker
Automated Description
Not Available
MGI Description
PHENOTYPE: Mice heterozygous for this mutation exhibit modifies lethality associated with F5 null Tfpi heterozygous mice. [provided by MGI curators]
Cross References
Not Available
Additional Information
Literature

Orthology

Gene tree
Not Available
No data available

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Must provide at least one subject
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Download all Alleles/Variants for all genes of the species

        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
          F5tm2Dgi/F5tm2Dgi MF5L6/MF5L6+ Tfpitm1Gjb/Tfpi+ [background:] involves: 129S1/Sv * 129S2/SvPas * C57BL/6
          • preweaning lethality, incomplete penetrance
          		MGI
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          Sequence Feature Viewer

          No data available

          Sequence Details

          Transcript: Mode:

          Expression

          Primary Sources
          None
          Other Sources
          Must provide at least one subject
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          MF5L6 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            MF5L6 role
            MF5L6 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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