Gene

Btg1

Species
Mus musculus
Symbol
Btg1
Name
BTG anti-proliferation factor 1
Synonyms
  • AI426953
  • AW546738
Biotype
protein coding gene
Automated Description
Predicted to enable enzyme binding activity. Acts upstream of or within negative regulation of cell population proliferation and protein methylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; central nervous system; limb; non-neural ectoderm; and sensory organ. Orthologous to human BTG1 (BTG anti-proliferation factor 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal neurogenesis in the dentate gyrus, decreased proliferation and increased apoptosis in the dentate gyrus and subventricular zone, impaired spatial learning and abnormal contextual conditioning behavior. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22978
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
96.453M96.454M96.455M96.456M96.457M96.458M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions