Gene

Cd72

Species
Mus musculus
Symbol
Cd72
Name
CD72 antigen
Synonyms
  • B-lymphocyte antigen 2
  • Ly-19
Biotype
protein coding gene
Automated Description
Predicted to enable carbohydrate binding activity and transmembrane signaling receptor activity. Predicted to be active in plasma membrane. Is expressed in brain; cerebellum external granule cell layer; cerebellum internal granule cell layer; hippocampus; and neocortex. Orthologous to human CD72 (CD72 molecule).
MGI Description
PHENOTYPE: Homozygous mutation of this gene results in impaired B cell development and delayed maturation, resulting in reduced numbers of mature B cells and an expansion of pre-B cells. Mice have fewer peripheral mature B-2 cells and more B-1 cells. B cells are hyperproliferative in response to stimuli. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR15028
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
43.448M43.449M43.450M43.451M43.452M43.453M43.454M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions