Gene

Cyp2f2

Species
Mus musculus
Symbol
Cyp2f2
Name
cytochrome P450, family 2, subfamily f, polypeptide 2
Synonyms
  • Cyp2f
  • Cyp2f1
Biotype
protein coding gene
Automated Description
Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Acts upstream of or within naphthalene catabolic process and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; nose; pharyngo-tympanic tube; respiratory system; and sublingual gland primordium. Orthologous to several human genes including CYP2F1 (cytochrome P450 family 2 subfamily F member 1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele exhibit resistance to napthalene-induced toxicity in the lungs. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24300
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
26.820M26.822M26.824M26.826M26.828M26.830M26.832M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions