Acts upstream of or within myotube cell development. Part of Cul4-RING E3 ubiquitin ligase complex. Is expressed in several structures, including cerebral cortex; liver; lung; metanephros; and spleen. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8).