Gene

Cidec

Species
Mus musculus
Symbol
Cidec
Name
cell death-inducing DFFA-like effector c
Synonyms
  • CIDE-3
  • CIDE-3alpha
Biotype
protein coding gene
Automated Description
Enables lipid transfer activity; molecular condensate scaffold activity; and phospholipid binding activity. Involved in lipid droplet fusion; lipid storage; and negative regulation of lipid metabolic process. Is active in lipid droplet. Is expressed in several structures, including alimentary system; endocrine gland; genitourinary system; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 5. Orthologous to human CIDEC (cell death inducing DFFA like effector c).
MGI Description
PHENOTYPE: Nullizygous mice exhibit leaness, high energy expenditure, improved glucose tolerance, altered brown adipocytes, and multilocular fat droplets with enhanced mitochondrial activity and lipolysis in white adipocytes, and may show resistance to age related and diet-induced obesity and liver steatosis. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12306
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
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113.402M113.403M113.404M113.405M113.406M113.407M113.408M113.409M113.410M113.411M113.412M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions