Gene

Gabrr1

Species
Mus musculus
Symbol
Gabrr1
Name
gamma-aminobutyric acid type A receptor subunit rho 1
Synonyms
  • GABA-C
Biotype
protein coding gene
Automated Description
Enables ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Involved in modulation of chemical synaptic transmission. Located in plasma membrane. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and presynaptic membrane. Is expressed in brain; cerebral cortex; and retina. Orthologous to human GABRR1 (gamma-aminobutyric acid type A receptor subunit rho1).
MGI Description
PHENOTYPE: Mice homozygous for a knock-out allele display altered visual processing in the retina. Mice homozygous for a different knock-out allele exhibit alterations of mechanical pain sensitivity, GABA-inhibited spinal cord responses, and olfactory function. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18945
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
33.135M33.140M33.145M33.150M33.155M33.160M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions