Gene

Ky

Species
Mus musculus
Symbol
Ky
Name
kyphoscoliosis peptidase
Synonyms
  • D9Mgc44e
  • DNA segment, Chr 9, MRC UK Mouse Genome Centre 44 expressed
Biotype
protein coding gene
Automated Description
Predicted to enable peptidase activity. Acts upstream of or within muscle organ development and neuromuscular junction development. Located in Z disc. Human ortholog(s) of this gene implicated in myofibrillar myopathy 7. Orthologous to human KY (kyphoscoliosis peptidase).
MGI Description
PHENOTYPE: Homozygotes for a spontaneous mutation exhibit severe degenerative myopathy involving postural muscles, resulting in thoraco-lumbar kyphoscoliosis with degenerative changes in intervertebral discs. Body weight is reduced and breathing is irregular. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46333
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
102.385M102.390M102.395M102.400M102.405M102.410M102.415M102.420M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions