Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within regulation of inner ear auditory receptor cell differentiation. Predicted to be located in chromosome and nucleoplasm. Is expressed in several structures, including central nervous system; foot bone; foregut; genitourinary system; and sensory organ. Orthologous to several human genes including MYCL (MYCL proto-oncogene, bHLH transcription factor).
MGI Description
PHENOTYPE: Mice homozygous for a targeted null allele are viable, fertile and apparently healthy with no congenital defects or gross morphological/cellular alterations of the CNS, lung, kidney and GI tract. [provided by MGI curators]