Gene

Gbp4

Species
Mus musculus
Symbol
Gbp4
Name
guanylate binding protein 4
Synonyms
  • AW228052
  • expressed sequence AW228052
Biotype
protein coding gene
Automated Description
Enables ubiquitin-protein transferase inhibitor activity. Involved in negative regulation of interferon-alpha production. Acts upstream of or within several processes, including cellular response to type II interferon; negative regulation of macromolecule metabolic process; and negative regulation of protein import into nucleus. Predicted to be located in Golgi membrane; nucleus; and perinuclear region of cytoplasm. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP6 (guanylate binding protein family member 6).
MGI Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10751
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
105.264M105.266M105.268M105.270M105.272M105.274M105.276M105.278M105.280M105.282M105.284M105.286M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions