Predicted to enable G-protein alpha-subunit binding activity; calcium ion binding activity; and guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of protein targeting and small GTPase-mediated signal transduction. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and extracellular space. Predicted to be extrinsic component of Golgi membrane. Predicted to be active in endoplasmic reticulum-Golgi intermediate compartment. Is expressed in atrioventricular valve; cochlea; and semilunar valve. Orthologous to human NUCB1 (nucleobindin 1).