Gene

Slc6a6

Species
Mus musculus
Symbol
Slc6a6
Name
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
Synonyms
  • AA589629
  • C80501
Biotype
protein coding gene
Automated Description
Enables beta-alanine transmembrane transporter activity; gamma-aminobutyric acid:sodium:chloride symporter activity; and taurine:sodium symporter activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within beta-alanine transport and taurine transmembrane transport. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in several structures, including brain; cardiovascular system; retina; spinal cord mantle layer; and tooth. Used to study retinitis pigmentosa. Orthologous to human SLC6A6 (solute carrier family 6 member 6).
MGI Description
PHENOTYPE: Homozygous mutant mice have impaired vision associated with retinal degeneration. In addition to the visual defects, mutant mice exhibit reduced female fertility and decreased levels of taurine in a variety of tissues. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11616
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
91.67M91.68M91.69M91.70M91.71M91.72M91.73M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions