Species | Gene symbol | Count | Best | Best reverse | Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN |
---|---|---|---|---|---|
Homo sapiens | TCF4 | 10 of 10 | Yes | Yes | ☑☑☑☑☑☑☑☑☑☑ |
Rattus norvegicus | Tcf4 | 9 of 9 | Yes | Yes | ☑ ☑☑☑☑☑☑☑☑ |
Xenopus tropicalis | tcf4 | 5 of 9 | Yes | Yes | ☑ ☐☐☑☑☐☑☑☐ |
Danio rerio | tcf4 | 1 of 10 | Yes | Yes | ☐ ☐☐☐☐☐☐☐☐ ☑ |
Drosophila melanogaster | da | 8 of 9 | Yes | Yes | ☑ ☑☑☐☑☑☑☑☑ |
Caenorhabditis elegans | hlh-2 | 5 of 9 | Yes | Yes | ☑ ☐☑☐☑☑☑☐☐ |
Phenotype Term | Annotation details | References |
---|---|---|
abnormal action potential | ||
abnormal associative learning | ||
abnormal B cell differentiation | ||
abnormal brain development | ||
abnormal brain morphology | ||
abnormal corpus callosum morphology | ||
abnormal dentate gyrus morphology | ||
abnormal gait | ||
abnormal habituation to a new environment | ||
abnormal long-term spatial reference memory |
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
---|---|---|---|---|---|---|---|
Mus musculus | Tg(Thy1-Tcf4)1Mjro | Yes | Yes |
Tcf4 molecule type | Interactor gene | Interactor species | Interactor molecule type | Detection methods | Source | Reference |
---|---|---|---|---|---|---|
protein | ASCL3 | Homo sapiens | protein |
| PMID:11784080 | |
protein | Ascl3 | Mus musculus | protein |
| PMID:11784080 | |
protein | ato | Drosophila melanogaster | protein |
| PMID:17878293 | |
protein | ato | Drosophila melanogaster | protein |
| PMID:17878293 | |
protein | Atoh1 | Mus musculus | protein |
| PMID:17878293 | |
protein | Atoh1 | Mus musculus | protein |
| PMID:17878293 | |
protein | Cbfa2t3 | Mus musculus | protein |
| PMID:16407974 | |
protein | Cbfa2t3 | Mus musculus | protein |
| PMID:16407974 | |
protein | CCNF | Homo sapiens | protein |
| PMID:36114006 | |
protein | Ctnnb1 | Mus musculus | protein |
| PMID:15578569 |
Tcf4 role | Tcf4 genetic perturbation | Interactor gene | Interactor species | Interactor role | Interactor genetic perturbation | Interaction type | Phenotype or trait | Source | Reference |
---|---|---|---|---|---|---|---|---|---|
suppressor gene | Ctnnb1 | Mus musculus | suppressed gene | phenotypic suppression (sensu BioGRID) |
| PMID:16478791 | |||
suppressor gene | Hras | Mus musculus | suppressed gene | phenotypic suppression (sensu BioGRID) |
| PMID:16478791 | |||
suppressor gene | Wnt11 | Mus musculus | suppressed gene | phenotypic suppression (sensu BioGRID) |
| PMID:19213727 |