Gene

Zbtb1

Species
Rattus norvegicus
Symbol
Zbtb1
Name
zinc finger and BTB domain containing 1
Synonyms
  • zinc finger and BTB domain-containing protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; K63-linked polyubiquitin modification-dependent protein binding activity; and protein dimerization activity. Predicted to be involved in several processes, including nucleobase-containing compound biosynthetic process; positive regulation of lymphocyte differentiation; and regulation of gene expression. Predicted to act upstream of or within B cell differentiation and T cell differentiation in thymus. Predicted to be located in nuclear body and nuclear membrane. Predicted to be active in nucleoplasm. Orthologous to human ZBTB1 (zinc finger and BTB domain containing 1).
RGD Description
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; K63-linked polyubiquitin modification-dependent protein binding activity; and protein dimerization activity. Predicted to be involved in several processes, including mRNA transcription by RNA polymerase II; positive regulation of lymphocyte differentiation; and regulation of gene expression. Predicted to act upstream of or within B cell differentiation and T cell differentiation in thymus. Predicted to be located in nuclear body and nuclear membrane. Predicted to be active in nucleoplasm. Orthologous to human ZBTB1 (zinc finger and BTB domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24394
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
95.100M95.105M95.110M95.115M95.120M95.125M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions