Version: 8.0.0Date: Tue Jan 28 2025
Gene
Tfap2c
- Species
- Rattus norvegicus
- Symbol
- Tfap2c
- Name
- transcription factor AP-2 gamma
- Synonyms
- activating enhancer binding protein 2 gamma
- activator protein 2 gamma
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in male gonad development; regulation of cell population proliferation; and regulation of gene expression. Predicted to act upstream of or within several processes, including branch elongation involved in mammary gland duct branching; forebrain development; and keratinocyte development. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TFAP2C (transcription factor AP-2 gamma).
- RGD Description
- Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in male gonad development; regulation of cell population proliferation; and regulation of gene expression. Predicted to act upstream of or within several processes, including branch elongation involved in mammary gland duct branching; forebrain development; and keratinocyte development. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TFAP2C (transcription factor AP-2 gamma); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR10812
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- None
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr3:161315031...161322998 + (7.97 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.