Gene

Hsd17b11

Species
Rattus norvegicus
Symbol
Hsd17b11
Name
hydroxysteroid (17-beta) dehydrogenase 11
Synonyms
  • 17-beta-HSD 11
  • 17-beta-HSD XI
Biotype
protein coding gene
Automated Description
Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Predicted to be involved in androgen catabolic process. Predicted to be located in cytoplasm. Predicted to be active in lipid droplet. Orthologous to human HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11).
RGD Description
Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Predicted to be involved in androgen catabolic process. Predicted to be located in cytoplasm. Predicted to be active in lipid droplet. Orthologous to human HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24322
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensHSD17B1110 of 10YesYes  
Mus musculusHsd17b119 of 9YesYes   
Xenopus tropicalissynj2bp8 of 9YesYes   
Xenopus tropicalishsd17b118 of 9YesYes   
Drosophila melanogasterCG92656 of 9YesYes   
Drosophila melanogasterLdsdh13 of 9NoYes   
Saccharomyces cerevisiaeYDL114W7 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Hsd17b13129880637 of 9 
Rdh10229854407 of 9 
Sdr16c5327364456 of 9 
Sdr16c6429856406 of 9 
Dhrs3528457355 of 9 
Hsd17b3631144252 of 9 
Hsd11b1727348282 of 9 
Hsd17b2829743272 of 9 
Rdh16929044272 of 9 
Hsd17b121029645242 of 9 
Rdh121130140272 of 9 
Sdr9c71230242242 of 9 
Hsd11b21327742282 of 9 
Rdh51429241252 of 9 
Rdh111525146282 of 9 
Dhrs91627143252 of 9 
Hsd17b11728537282 of 9 
Kdsr1827242242 of 9 
Hsd17b101926241242 of 9 
Hsd17b62025241272 of 9 
Bdh12123544282 of 9 
Hsdl12222445282 of 9 
Hsd17b142325739242 of 9 
Hsd17b82425040222 of 9 
Hsd17b42522043252 of 9 
Hsd17b72623437232 of 9 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
mRatBN7.2
Viewer Help
5.695M5.700M5.705M5.710M5.715M5.720M5.725M5.730M5.735M5.740M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
NC_051349.1:g.5695848A>Gvariant
SNP
  • intron variant
NC_051349.1:g.5696805A>Tvariant
SNP
  • intron variant
NC_051349.1:g.5704587G>Tvariant
SNP
  • intron variant
NC_051349.1:g.5717447A>Gvariant
SNP
  • intron variant
NC_051349.1:g.5726911G>Cvariant
SNP
  • intron variant
NC_051349.1:g.5735531A>Gvariant
SNP
  • intron variant
NC_051349.1:g.5715859T>Cvariant
SNP
  • intron variant
NC_051349.1:g.5729517T>Cvariant
SNP
  • intron variant
NC_051349.1:g.5729549G>Avariant
SNP
  • intron variant
NC_051349.1:g.5731679G>Avariant
SNP
  • intron variant
Showing 1 - 10 of 257 rows
per page

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
5.695M5.700M5.705M5.710M5.715M5.720M5.725M5.730M5.735M5.740MENSRNOT00000003004.7 (Hsd17b11)NM_001004209.1 (Hsd17b11)XM_006250627.5 (Hsd17b11)XM_006250629.5 (Hsd17b11)ENSRNOT00000002973.5 (Nudt9)NM_001006991.1 (Nudt9)XM_006250630.4 (Nudt9)XM_006250631.5 (Nudt9)XM_017599163.3 (Nudt9)

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available