Gene

Clec4d

Species
Rattus norvegicus
Symbol
Clec4d
Name
C-type lectin domain family 4, member D
Synonyms
  • C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8
  • C-type lectin domain family 4 member D
Biotype
protein coding gene
Automated Description
Predicted to enable D-mannose binding activity; immunoglobulin receptor binding activity; and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of myeloid dendritic cell activation. Predicted to act upstream of or within several processes, including Fc-gamma receptor signaling pathway; T cell differentiation involved in immune response; and defense response to other organism. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4D (C-type lectin domain family 4 member D).
RGD Description
Predicted to enable D-mannose binding activity; immunoglobulin receptor binding activity; and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of myeloid dendritic cell activation. Predicted to act upstream of or within several processes, including Fc-gamma receptor signaling pathway; T cell differentiation involved in immune response; and defense response to other organism. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC4D (C-type lectin domain family 4 member D); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,7-dihydropurine-6-thione.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46746
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
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            156.590M156.591M156.592M156.593M156.594M156.595M156.596M156.597M156.598M156.599M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Clec4d molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              Clec4d role
              Clec4d genetic perturbation
              Interactor gene
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              Interactor role
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