ATG14 autophagy related 14 homolog (S. cerevisiae)
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Predicted to be involved in several processes, including early endosome to late endosome transport; macroautophagy; and regulation of protein phosphorylation. Predicted to act upstream of or within defense response to symbiont; endosome to lysosome transport; and regulation of triglyceride metabolic process. Predicted to be located in several cellular components, including mitochondria-associated endoplasmic reticulum membrane contact site; phagocytic vesicle; and phagophore assembly site membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class III. Predicted to be active in autophagosome and phagophore assembly site. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Orthologous to human ATG14 (autophagy related 14).
RGD Description
Predicted to enable GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Predicted to be involved in several processes, including early endosome to late endosome transport; macroautophagy; and regulation of protein phosphorylation. Predicted to act upstream of or within defense response to symbiont; endosome to lysosome transport; and regulation of triglyceride metabolic process. Predicted to be located in several cellular components, including mitochondria-associated endoplasmic reticulum membrane contact site; phagocytic vesicle; and phagophore assembly site membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class III. Predicted to be active in autophagosome and phagophore assembly site. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Orthologous to human ATG14 (autophagy related 14); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.