Gene

Atg14

Species
Rattus norvegicus
Symbol
Atg14
Name
autophagy related 14
Synonyms
  • ATG14 autophagy related 14 homolog
  • ATG14 autophagy related 14 homolog (S. cerevisiae)
Biotype
protein coding gene
Automated Description
Predicted to enable GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Predicted to be involved in several processes, including early endosome to late endosome transport; macroautophagy; and regulation of protein phosphorylation. Predicted to act upstream of or within defense response to symbiont; endosome to lysosome transport; and regulation of triglyceride metabolic process. Predicted to be located in several cellular components, including mitochondria-associated endoplasmic reticulum membrane contact site; phagocytic vesicle; and phagophore assembly site membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class III. Predicted to be active in autophagosome and phagophore assembly site. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Orthologous to human ATG14 (autophagy related 14).
RGD Description
Predicted to enable GTPase binding activity; phosphatidylinositol 3-kinase inhibitor activity; and protein-membrane adaptor activity. Predicted to be involved in several processes, including early endosome to late endosome transport; macroautophagy; and regulation of protein phosphorylation. Predicted to act upstream of or within defense response to symbiont; endosome to lysosome transport; and regulation of triglyceride metabolic process. Predicted to be located in several cellular components, including mitochondria-associated endoplasmic reticulum membrane contact site; phagocytic vesicle; and phagophore assembly site membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class III. Predicted to be active in autophagosome and phagophore assembly site. Predicted to be extrinsic component of omegasome membrane and extrinsic component of phagophore assembly site membrane. Orthologous to human ATG14 (autophagy related 14); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13664
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
20.800M20.805M20.810M20.815M20.820M20.825M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions