Gene

Castor2

Species
Rattus norvegicus
Symbol
Castor2
Name
cytosolic arginine sensor for mTORC1 subunit 2
Synonyms
  • Gats
  • GATS protein-like 2
Biotype
protein coding gene
Automated Description
Predicted to enable identical protein binding activity. Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2).
RGD Description
Predicted to enable identical protein binding activity. Predicted to be involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol. Orthologous to several human genes including CASTOR2 (cytosolic arginine sensor for mTORC1 subunit 2); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR31131
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
22.580M22.585M22.590M22.595M22.600M22.605M22.610M22.615M22.620M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions