Gene

Ppp2r1b

Species
Rattus norvegicus
Symbol
Ppp2r1b
Name
protein phosphatase 2 scaffold subunit A beta
Synonyms
  • LOC315648
  • PP2A subunit A isoform PR65-beta
Biotype
protein coding gene
Automated Description
Predicted to enable protein phosphatase regulator activity. Predicted to be involved in several processes, including meiotic sister chromatid cohesion, centromeric; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and spindle assembly. Predicted to be located in membrane raft. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol; glutamatergic synapse; and nucleus. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human PPP2R1B (protein phosphatase 2 scaffold subunit Abeta).
RGD Description
Predicted to enable protein phosphatase regulator activity. Predicted to be involved in apoptotic process involved in morphogenesis; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and protein dephosphorylation. Predicted to be located in membrane raft. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol; glutamatergic synapse; and nucleus. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human PPP2R1B (protein phosphatase 2 scaffold subunit Abeta); PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; Chagas disease pathway; hepatitis C pathway; INTERACTS WITH 1,3-dinitrobenzene; 6-propyl-2-thiouracil; amitrole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10648
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
51.190M51.195M51.200M51.205M51.210M51.215M51.220M51.225M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions