Gene

Wdr24

Species
Rattus norvegicus
Symbol
Wdr24
Name
WD repeat domain 24
Synonyms
  • GATOR complex protein WDR24
  • GATOR2 complex protein WDR24
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; positive regulation of TORC1 signaling; and protein K6-linked ubiquitination. Predicted to act upstream of or within positive regulation of protein kinase activity. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol and vacuolar membrane. Orthologous to human WDR24 (WD repeat domain 24).
RGD Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; positive regulation of TORC1 signaling; and protein K6-linked ubiquitination. Predicted to act upstream of or within positive regulation of protein kinase activity. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol and vacuolar membrane. Orthologous to human WDR24 (WD repeat domain 24); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46200
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions