Gene

Mrtfa

Species
Rattus norvegicus
Symbol
Mrtfa
Name
myocardin related transcription factor A
Synonyms
  • basic, SAP, and coiled-coil domain containing protein
  • BSAC
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including actin monomer binding activity; leucine zipper domain binding activity; and transcription coactivator activity. Involved in regulation of modification of postsynaptic structure and regulation of transcription by RNA polymerase II. Is active in glutamatergic synapse; postsynapse; and presynapse. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A).
RGD Description
Predicted to enable several functions, including actin monomer binding activity; leucine zipper domain binding activity; and transcription coactivator activity. Involved in regulation of modification of postsynaptic structure and regulation of transcription by RNA polymerase II. Is active in glutamatergic synapse; postsynapse; and presynapse. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22793
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
112.56M112.58M112.60M112.62M112.64M112.66M112.68M112.70M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions