Gene

Il27ra

Species
Rattus norvegicus
Symbol
Il27ra
Name
interleukin 27 receptor subunit alpha
Synonyms
  • interleukin 27 receptor, alpha
  • interleukin-27 receptor subunit alpha
Biotype
protein coding gene
Automated Description
Predicted to enable interleukin-27 receptor activity. Predicted to be involved in several processes, including negative regulation of T cell extravasation; negative regulation of T-helper 17 type immune response; and negative regulation of cytokine production. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of type II interferon production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha).
RGD Description
Predicted to enable cytokine binding activity and interleukin-27 receptor activity. Predicted to be involved in several processes, including negative regulation of T cell extravasation; negative regulation of T-helper 17 type immune response; and negative regulation of cytokine production. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of type II interferon production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR48335
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
24.110M24.112M24.114M24.116M24.118M24.120M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions