Predicted to enable interleukin-27 receptor activity. Predicted to be involved in several processes, including negative regulation of T cell extravasation; negative regulation of T-helper 17 type immune response; and negative regulation of cytokine production. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of type II interferon production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha).
RGD Description
Predicted to enable cytokine binding activity and interleukin-27 receptor activity. Predicted to be involved in several processes, including negative regulation of T cell extravasation; negative regulation of T-helper 17 type immune response; and negative regulation of cytokine production. Predicted to act upstream of or within several processes, including defense response to Gram-positive bacterium; positive regulation of type II interferon production; and regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Orthologous to human IL27RA (interleukin 27 receptor subunit alpha); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol.