bromodomain adjacent to zinc finger domain protein 2A
LOC304601
Biotype
protein coding gene
Automated Description
Predicted to enable chromatin-protein adaptor activity; lysine-acetylated histone binding activity; and nucleic acid binding activity. Predicted to contribute to RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase I. Predicted to act upstream of or within rDNA heterochromatin formation. Predicted to be located in cytosol; nuclear lumen; and rDNA heterochromatin. Predicted to be part of NoRC complex and chromatin silencing complex. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A).
RGD Description
Predicted to enable chromatin-protein adaptor activity; lysine-acetylated histone binding activity; and nucleic acid binding activity. Predicted to contribute to RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase I. Predicted to act upstream of or within rDNA heterochromatin formation. Predicted to be located in cytosol; nuclear lumen; and rDNA heterochromatin. Predicted to be part of NoRC complex and chromatin silencing complex. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; amphetamine.