Version: 8.0.0
Date: Tue Jan 28 2025
Pibf1
Rattus norvegicusRGD:1305077
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Pibf1

Species
Rattus norvegicus
Symbol
Pibf1
Name
progesterone immunomodulatory binding factor 1
Synonyms
  • LOC306104
  • progesterone-induced-blocking factor 1
Biotype
protein coding gene
Automated Description
Predicted to enable identical protein binding activity and interleukin-4 receptor binding activity. Predicted to be involved in several processes, including mitotic sister chromatid segregation; regulation of biosynthetic process; and regulation of protein phosphorylation. Predicted to be located in centriolar satellite; extracellular space; and nucleus. Predicted to be active in microtubule organizing center. Human ortholog(s) of this gene implicated in Joubert syndrome 33. Orthologous to human PIBF1 (progesterone immunomodulatory binding factor 1).
RGD Description
Predicted to enable identical protein binding activity and interleukin-4 receptor binding activity. Predicted to be involved in several processes, including mitotic sister chromatid segregation; regulation of cytokine production; and regulation of protein phosphorylation. Predicted to be located in centriolar satellite; extracellular space; and nucleus. Predicted to be active in microtubule organizing center. Human ortholog(s) of this gene implicated in Joubert syndrome 33. Orthologous to human PIBF1 (progesterone immunomodulatory binding factor 1); INTERACTS WITH bisphenol A; diuron; glyphosate.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18950
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          mRatBN7.2
          Viewer Help
          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          None
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Pibf1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            Pibf1 role
            Pibf1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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