Version: 8.1.0Date: Fri Apr 18 2025
Gene
Kifap3
- Species
- Rattus norvegicus
- Symbol
- Kifap3
- Name
- kinesin-associated protein 3
- Synonyms
- LOC289168
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable intraciliary transport particle B binding activity; kinesin binding activity; and protein phosphatase binding activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cilium organization. Predicted to act upstream of or within several processes, including negative regulation of apoptotic process; negative regulation of neuroblast proliferation; and positive regulation of calcium-dependent cell-cell adhesion. Predicted to be located in several cellular components, including microtubule cytoskeleton; periciliary membrane compartment; and photoreceptor cell cilium. Predicted to be part of kinesin II complex. Predicted to be active in several cellular components, including axoneme; ciliary transition zone; and glutamatergic synapse. Orthologous to human KIFAP3 (kinesin associated protein 3).
- RGD Description
- Predicted to enable intraciliary transport particle B binding activity; kinesin binding activity; and protein phosphatase binding activity. Predicted to be involved in anterograde dendritic transport of neurotransmitter receptor complex and cilium organization. Predicted to act upstream of or within several processes, including negative regulation of apoptotic process; negative regulation of neuroblast proliferation; and positive regulation of calcium-dependent cell-cell adhesion. Predicted to be located in several cellular components, including microtubule cytoskeleton; periciliary membrane compartment; and photoreceptor cell cilium. Predicted to be part of kinesin II complex. Predicted to be active in several cellular components, including axoneme; ciliary transition zone; and glutamatergic synapse. Orthologous to human KIFAP3 (kinesin associated protein 3); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR15605
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- None
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr13:76127696...76264654 + (136.96 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.