Version: 8.1.0Date: Fri Apr 18 2025
Gene
Trim32
- Species
- Rattus norvegicus
- Symbol
- Trim32
- Name
- tripartite motif-containing 32
- Synonyms
- E3 ubiquitin-protein ligase TRIM32
- LOC313264
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable several functions, including identical protein binding activity; transcription coactivator activity; and ubiquitin binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of metabolic process; and regulation of signal transduction. Predicted to act upstream of or within several processes, including muscle cell cellular homeostasis; positive regulation of chemokine (C-C motif) ligand 20 production; and protein ubiquitination. Predicted to be located in nucleus and striated muscle myosin thick filament. Predicted to be active in autophagosome and centrosome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32).
- RGD Description
- Predicted to enable several functions, including identical protein binding activity; transcription coactivator activity; and ubiquitin binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of metabolic process; and regulation of signal transduction. Predicted to act upstream of or within several processes, including muscle cell cellular homeostasis; positive regulation of chemokine (C-C motif) ligand 20 production; and protein ubiquitination. Predicted to be located in nucleus and striated muscle myosin thick filament. Predicted to be active in autophagosome and centrosome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 11; autosomal recessive limb-girdle muscular dystrophy type 2H; and muscular dystrophy. Orthologous to human TRIM32 (tripartite motif containing 32); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR25464
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- None
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr5:78999389...79022018 + (22.63 kb)
- Assembly version
- mRatBN7.2
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- None
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.