Predicted to enable DNA binding activity; enzyme binding activity; and histone binding activity. Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA metabolic process; apoptotic process; and cochlea development. Predicted to act upstream of or within cellular response to interleukin-4 and nucleosome assembly. Predicted to be located in chromatin; cytoplasm; and nucleoplasm. Predicted to be part of CMG complex; MCM complex; and nuclear origin of replication recognition complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Orthologous to human MCM2 (minichromosome maintenance complex component 2).
RGD Description
Predicted to enable DNA binding activity; enzyme binding activity; and histone binding activity. Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA metabolic process; apoptotic process; and cochlea development. Predicted to act upstream of or within cellular response to interleukin-4 and nucleosome assembly. Predicted to be located in chromatin; cytoplasm; and nucleoplasm. Predicted to be part of CMG complex; MCM complex; and nuclear origin of replication recognition complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Orthologous to human MCM2 (minichromosome maintenance complex component 2); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.