Predicted to enable several functions, including NAD+ binding activity; NAD-dependent protein lysine deacylase activity; and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Predicted to be involved in several processes, including chromatin remodeling; protein deacylation; and regulation of macromolecule metabolic process. Predicted to be located in nuclear speck; nucleolus organizer region; and site of double-strand break. Predicted to be active in nucleus. Orthologous to human SIRT7 (sirtuin 7).
RGD Description
Predicted to enable several functions, including chromatin binding activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; and protein-propionyllysine depropionylase activity. Predicted to be involved in several processes, including chromatin remodeling; protein deacylation; and regulation of gene expression. Predicted to be located in nuclear speck; nucleolus organizer region; and site of double-strand break. Predicted to be active in nucleus. Orthologous to human SIRT7 (sirtuin 7); PARTICIPATES IN histone modification pathway; RNA polymerase I transcription pathway; Sirtuin mediated pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.