Gene

Sec61a2

Species
Rattus norvegicus
Symbol
Sec61a2
Name
SEC61 translocon subunit alpha 2
Synonyms
  • LOC361273
  • Sec61 alpha 2 subunit
Biotype
protein coding gene
Automated Description
Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be part of Sec61 translocon complex. Orthologous to human SEC61A2 (SEC61 translocon subunit alpha 2).
RGD Description
Predicted to enable protein transmembrane transporter activity; ribosome binding activity; and signal sequence binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation and post-translational protein targeting to membrane, translocation. Predicted to be part of Sec61 translocon complex. Orthologous to human SEC61A2 (SEC61 translocon subunit alpha 2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; phagocytosis pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; difenoconazole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10906
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
72.410M72.415M72.420M72.425M72.430M72.435M72.440M72.445M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions