Gene

Atad3a

Species
Rattus norvegicus
Symbol
Atad3a
Name
ATPase family, AAA domain containing 3A
Synonyms
  • Atad3
  • ATPase family AAA domain-containing protein 3
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and identical protein binding activity. Predicted to be involved in several processes, including antiviral innate immune response; negative regulation of PERK-mediated unfolded protein response; and regulation of cell growth. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondria-associated endoplasmic reticulum membrane contact site and mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Harel-Yoon syndrome and neonatal lethal pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome. Orthologous to several human genes including ATAD3A (ATPase family AAA domain containing 3A).
RGD Description
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including antiviral innate immune response; mitochondrion organization; and regulation of cell growth. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Harel-Yoon syndrome and neonatal lethal pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome. Orthologous to several human genes including ATAD3A (ATPase family AAA domain containing 3A); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23075
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
166.352M166.354M166.356M166.358M166.360M166.362M166.364M166.366M166.368M166.370M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions